His style aligns with the Federal period of American art. Ames focused on clarity and formal composition. He often used neutral backgrounds to ensure the viewer remained fixed on the subject. Portraits like those of William James or John Scoville avoid unnecessary flourish. Technical analysis, including X-rays of his portrait of Mrs. Spencer, reveals a methodical approach to layering paint. This precision suggests a level of honesty in his depictions of the early American merchant class.

Modern collectors value the architectural quality of his work. These portraits possess a structured appearance that suits both traditional and minimalist interiors. The lack of excessive ornamentation allows the historical character of the sitter to remain the primary interest. An Ezra Ames print provides a sense of permanence and historical continuity for a contemporary home.