A Renaissance portrait by Lorenzo Lotto depicting Lucina Brembati, featuring a distinctive crescent moon symbol and detailed period attire.

Lorenzo Lotto, a Venetian painter active during the High Renaissance, produced this portrait of Lucina Brembati around 1518. The subject is depicted in a half-length pose, wearing a dark gown with a white bodice adorned with gold embroidery. Her attire includes a red headpiece decorated with small gold bows and a string of pearls. A notable detail is the pendant hanging from her gold chain, which features a horn-shaped charm, a common protective amulet of the period. Her left hand rests near a small, dark animal, often identified as a marten or weasel, which was a fashionable accessory for noblewomen at the time.

The background contains a curious element: a crescent moon in the upper left corner. Within the moon, the letters 'CI' are visible, which scholars have interpreted as a rebus for the sitter's name, 'Lucina'. This inclusion of symbolic or cryptic imagery is characteristic of Lotto's approach to portraiture, where he often integrated personal references or psychological depth beyond mere physical likeness. The lighting is focused on the sitter's face and hands, creating a contrast against the darker, atmospheric background.

Lotto was known for his idiosyncratic style, which diverged from the more classical norms of his contemporaries in Venice. His work often displays a keen attention to texture and detail, from the sheen of the pearls to the fabric of the garments. This portrait remains a representative example of his ability to capture the specific identity of his sitters while incorporating subtle, enigmatic motifs. The painting is currently held in the collection of the Accademia Carrara in Bergamo, reflecting the artist's strong connections to the region during his career.