His artistic approach relied on clear lines and careful observation. In Herberginterieur, he captured the atmosphere of a Dutch tavern with technical precision. His studies of the human form, such as his drawings of male nudes, demonstrate a strong foundation in academic training. He worked across various subjects, including architectural gates like the Poort te Ijsselstein and domestic scenes. This versatility allowed him to manage both formal commissions and more intimate observations of life.

Modern collectors value the work of Oosterhuis for its clean aesthetic and historical clarity. His prints offer a view into the Dutch Biedermeier period, a time that valued domesticity and social order. The balanced compositions suit contemporary interiors that prefer understated art. His depictions of family life, such as a mother with four children in a natural setting, provide a sense of calm. These pieces function as historical documents and decorative elements for a home.