His style follows late Dutch Baroque and early Rococo traditions. Sanders used a clear colour palette and focused on the physical texture of his subjects. In still life work like Druiventros, he captured the translucency of fruit and small details of nature. His historical scenes, such as Esther voor Ahasveros, demonstrate an ability to manage multiple figures and theatrical lighting. He often included small elements, like a single insect, to add realism to his compositions.

Modern collectors value Sanders for his versatility and the quiet precision of his smaller studies. His botanical and entomological works fit well in contemporary interiors that favour natural history themes. The neutral colours and balanced compositions of his portraits make them adaptable to various decor styles. His work provides a direct connection to the refined domestic aesthetics of the 18th-century Netherlands.