His artistic style is defined by a heavy, almost sculptural application of paint. In works such as Old Sea-captain and Waiting, Romano uses bold lines and a muted palette to define his subjects. He often focused on the human face, stripping away decorative elements to concentrate on form and expression. This approach is evident in his portraits of notable figures like Francis Henry Taylor and William Leonard Langer. His technique avoids the soft edges of Impressionism, preferring the solid, architectural qualities found in early Renaissance frescoes.

Modern collectors value Romano for his ability to convey character without relying on sentimentality. His paintings possess a gravity that suits contemporary interiors, offering a sense of permanence and weight. The starkness of his compositions allows his work to function as a strong visual anchor in a room. Because he moved between abstraction and realism, his prints appeal to those who appreciate the technical skill of traditional portraiture combined with a twentieth-century sensibility.