His style represents a bridge between Neoclassical structure and Romantic subject matter. Mercuri excelled at translating the textures of fabric and skin into the medium of line engraving. His portraits of historical figures like Columbus and T. Tasso demonstrate a sharp focus on character and costume. In works such as Reapers in the Pontine marshes, he applied this same rigour to scenes of daily life. He avoided the heavy cross-hatching common in his era, preferring clean, parallel lines to define form.

Modern collectors value Mercuri for the clarity and graphic strength of his work. His prints offer a sense of historical weight without the visual clutter of more ornamental styles. The monochromatic nature of his engravings makes them versatile for contemporary interior design. They provide a sophisticated link to the history of the Kingdom of Italy and the French academic tradition. These prints work well in a study or a hallway where their fine details can be observed closely.