His work is defined by a restrained palette and a focus on texture. He frequently painted 'ontbijtjes' or breakfast pieces, which featured items like pewter plates and half-filled wine glasses. Den Uyl was a master of capturing the way light reflects off metallic surfaces and the transparency of glass. He avoided the use of bright colours, preferring a tonal range of greys and muted browns. This approach creates a sense of stillness and order in his compositions.

Modern collectors value Den Uyl for his minimalist aesthetic and technical precision. His paintings do not rely on narrative or drama; instead, they offer a calm study of form and light. These works fit well in contemporary interiors because of their neutral colour schemes and balanced arrangements. A print of a Den Uyl still life provides a window into seventeenth-century Dutch domestic life while remaining stylistically relevant today.